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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC19A1
All Species:
4.85
Human Site:
S499
Identified Species:
10.67
UniProt:
P41440
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41440
NP_919231.1
591
64868
S499
G
G
L
Q
P
A
Q
S
P
P
L
S
P
E
D
Chimpanzee
Pan troglodytes
XP_001157360
590
64733
S498
G
G
L
Q
P
A
Q
S
P
L
L
S
P
E
D
Rhesus Macaque
Macaca mulatta
XP_001118114
475
51869
Q384
L
G
G
L
Q
P
A
Q
S
L
P
L
S
P
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P41438
512
58132
V421
K
R
G
L
G
L
Q
V
R
D
Q
F
R
I
Y
Rat
Rattus norvegicus
Q62866
512
58076
V421
K
R
G
L
G
L
Q
V
H
Q
Q
F
R
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521689
430
48416
F339
L
V
F
G
L
N
T
F
F
A
T
I
L
K
S
Chicken
Gallus gallus
NP_001006513
496
55568
E405
I
A
T
S
L
S
K
E
L
C
A
L
V
F
G
Frog
Xenopus laevis
NP_001085999
531
60307
F440
K
E
L
C
A
L
V
F
G
V
N
T
F
F
A
Zebra Danio
Brachydanio rerio
XP_002662447
528
59393
L437
V
F
G
V
N
T
F
L
G
T
I
L
K
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17766
410
46514
S319
N
V
A
K
E
L
S
S
N
N
H
G
L
I
F
Sea Urchin
Strong. purpuratus
XP_791719
533
60255
L441
L
P
A
D
T
Q
F
L
V
Y
G
G
Y
F
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
73.2
N.A.
N.A.
59.3
58.8
N.A.
47.3
53.4
51.4
52.1
N.A.
N.A.
N.A.
26.3
34.6
Protein Similarity:
100
99.1
74.7
N.A.
N.A.
68.5
68.1
N.A.
59
64.4
63.9
63.9
N.A.
N.A.
N.A.
40
51.4
P-Site Identity:
100
93.3
6.6
N.A.
N.A.
6.6
6.6
N.A.
0
0
6.6
0
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
93.3
13.3
N.A.
N.A.
6.6
6.6
N.A.
6.6
13.3
13.3
6.6
N.A.
N.A.
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
0
10
19
10
0
0
10
10
0
0
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
19
% D
% Glu:
0
10
0
0
10
0
0
10
0
0
0
0
0
19
10
% E
% Phe:
0
10
10
0
0
0
19
19
10
0
0
19
10
28
10
% F
% Gly:
19
28
37
10
19
0
0
0
19
0
10
19
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
10
10
0
28
10
% I
% Lys:
28
0
0
10
0
0
10
0
0
0
0
0
10
10
0
% K
% Leu:
28
0
28
28
19
37
0
19
10
19
19
28
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
10
0
0
10
10
10
0
0
0
0
% N
% Pro:
0
10
0
0
19
10
0
0
19
10
10
0
19
10
0
% P
% Gln:
0
0
0
19
10
10
37
10
0
10
19
0
0
0
0
% Q
% Arg:
0
19
0
0
0
0
0
0
10
0
0
0
19
0
0
% R
% Ser:
0
0
0
10
0
10
10
28
10
0
0
19
10
0
10
% S
% Thr:
0
0
10
0
10
10
10
0
0
10
10
10
0
0
0
% T
% Val:
10
19
0
10
0
0
10
19
10
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
28
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _